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The human brain has the ability to flexibly apply information perceived from experience to cognition and behavior in different areas. This ability is similar to the idea of ​​transfer learning (TL) used in the field of machine learning. Transfer learning can improve the performance of the model in a new area, even in situations where insufficient training data is available. In particular, transfer learning using an excellent machine learning model such as "Convolutional Neural Network (CNN)" Note 3 shows high ability to respond to various areas.
However, no matter how advanced transfer learning is used, it has not yet been realized that the machine learning model has the responsiveness comparable to that of the human brain. To solve this, we have developed "Brain-mediated TL (BTL)", a transfer learning method that mediates the human brain, in order to adapt the machine learning model to areas that require human-like cognition. BTL converts the audiovisual input information possessed by CNN into information representation based on individual brain activity patterns and uses it for transfer learning to estimate human cognition and behavior caused by audiovisual input. From this verification result, it was confirmed that BTL shows higher performance in cognitive / behavior estimation than standard transfer learning that does not mediate the brain. We have shown that using the brains of different people makes a difference in the estimation results by BTL, and that the difference may reflect the difference in perception among individuals.
From the above results, it was found that the use of BTL improves the ability of machine learning models to respond. BTL also hopes that machine learning will provide a technical framework that enables human-like cognition and behavior to be estimated, including

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Non-invasive detection of biological information by applying cutting-edge science and technology such as AI and optical technology
Research and development of advanced medical devices and physics and chemistry devices that contribute to medical care, and obtained many domestic and overseas patents, as well as medical device manufacturing and sales licenses
Applications (multipurpose biometric information measurement system)]
■ Medical field
・ General medical care
・ Monitor during treatment such as dialysis
・ Emergency medical monitor, etc.
■ Living field
・ Life watching (remote islands, long-term care, depopulation)
・ Watching over exercise, etc.
■ Industrial field
・ Watching over the driver
・ Watching underground work
■ Research field
・ Exercise physiology, etc.
■ OEM manufacturing of electronic equipment, labor-saving machinery for general industry, FA system, design and manufacture of test equipment
■ Research and development consignment (medical device manufacturing license number 23BZ6061)
(Medical device manufacturing and sales license number 23B2X90005)

We have been working on high quality and original technology development. In order to provide safe and convenient products, we have obtained many patents related to DX cutting-edge technology and development such as AIoT 5G blockchain quantum computing XR, AR, VR, etc., and will continue to be an "ICT company" ICT area (main areas: Fintech, communication [ AR / VR], security, media content, Bigdata, cloud, IoT / drone, marketing / advertising, medical / healthcare, robotics, power / battery, AI, Enterprise, education New energy industry (battery-related) battery (storage battery, hydrogen)・ We will continue to develop and evolve as (fuel cells, etc.) and battery materials / components, etc.). By field (environment / energy, life science, system / information science and technology, nanotechnology / materials), hardware / software development using cutting-edge technology, demonstration experiments, research and development / operation / sales of prototype products, by field ( Environment / Energy, Life Sciences, Systems / Information Science and Technology, Nanotechnology / Materials)

Realization of "ultra-smart society" (Society 5.0), "11 systems" that are said to be advanced toward its realization include "promotion of community-based comprehensive care system", "smart food chain system", "smart" "Production system" is included. In addition, among the issues that should be strategically resolved, there are several related matters such as stable food security, formation of a healthy and long-lived society by realizing the world's most advanced medical technology, and improvement of competitiveness in manufacturing and manufacturing. It has been. Regarding the above-mentioned research and development related to "formation of a healthy and long-lived society by realizing the world's most advanced medical technology", based on the health and medical strategy and medical field research and development promotion plan under the Health and Medical Strategy Promotion Headquarters. ,

The following nine main initiatives will be promoted as pillars. In addition, in other fields such as infectious disease control

We will promote international contributions, build a medical ICT infrastructure, and improve the environment for utilization.

All-Japan drug creation

All-Japan medical device development

Innovative medical technology creation base project

Realization of regenerative medicine Highway concept

Genome medical realization project for overcoming diseases

Japan Cancer Research Project

Brain and Mental Health Powerhouse Realization Project

Emerging and re-emerging infectious disease control project

R & D bird's-eye view report

R & D strategies of major countries (2020)

CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center

Intractable disease overcoming project

System / Information Science and Technology Field The Information Science and Technology field has been positioned as a common basic technology that supports green innovation, life innovation, and strengthening of industrial competitiveness. In addition, as science and technology that can be used across multiple fields and science and technology in the fusion field, nanotechnology, optical / quantum science and technology, advanced information and communication technology such as simulation and e-science, mathematical science, and system science. Promotion of technology research and development is mentioned, and as a concrete initiative, basic technology required for ultra-smart social service platform

As strong as cyber security, IoT system construction, big data analysis, AI, devices, etc.

Strong robots, sensors, light, quantum, etc. as basic technologies that will be the core of technology and new value creation

It is going to be changed. The four pillars are (1) social implementation of Society 5.0, (2) strengthening of research capabilities centered on basic research, (3) drastic strengthening of international cooperation, and (4) construction of priority strategies in cutting-edge and important fields such as AI technology and quantum technology. Was included. Nanotechnology / Materials field “Nanotechnology / Materials” is one of the four priority promotion fields, and resource allocation has been focused on for 10 years along with life sciences, information and communications, and the environment. The main achievements were as follows. "Discovery of new superconducting materials including iron", "Progress in development of various materials leading to practical use including carbon fiber composite materials", "Progress in research on molecular imaging", "National core technology" X-ray

Development of R & D infrastructure such as "free electron laser" and "nanotechnology network", "Oh

Industry-academia-government collaboration by Pun Innovation Center "Tsukuba Innovation Arena" (TIA-nano)

"Strengthening", "Ministry collaboration project:" Element strategy project "(Ministry of Education, Culture, Sports, Science and Technology) and" Rare metal alternative materials

"Project" (Ministry of Economy, Trade and Industry) steady progress ", etc. In the 4th term (2011-2015), 11 systems that contribute to the realization of the "super smart society" of RIKEN (Society 5.0) were identified from the priority area type of science and technology, and "Society 5.0" was identified as one of them. Integrated Material Development System ”Overview Report of Research and Development

R & D strategies of major countries (2020)

CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center

There are 28. To promote the creation of innovative functional materials, structural materials, etc. that make full use of computational science and data science.

In addition, with the goal of significantly shortening the development period, we are aware of the problem that nanotechnology and materials science and technology must continue to play a major role in the realization of Society 5.0 and SDGs. In August 2018, the Nanotechnology and Materials Science and Technology Committee of the Research Planning and Evaluation Subcommittee of the Science and Technology Council of the Ministry of Education, Culture, Sports, Science and Technology announced the "Social Revolution by Materials" that contributes to both industrial promotion and "happiness" of humankind. (Material Revolution) ”was announced with the goal of realizing the“ Nanotechnology / Materials Science and Technology Research and Development Strategy ”.

(3) Research infrastructure policy in the field of nanotechnology and materials

Tip. We provide cutting-edge research equipment and technical support to industry-academia-government users in three technical areas (microstructure analysis, microfabrication, and molecular / substance synthesis). It is operated by 38 institutions nationwide, including 11 institutions for microstructure analysis, 16 institutions for microfabrication, 10 institutions for molecular / substance synthesis, and a center agency responsible for overall coordination of the entire business. In addition, in collaboration with JST's ALCA next-generation storage battery project, the National Institute of Advanced Industrial Science and Technology will be in Tsukuba, where cutting-edge nanotechnology research facilities and human resources, which consist of three institutions, will be concentrated.

The National Institute for Materials Science, University of Tsukuba, High Energy Accelerator Research Organization, and the University of Tokyo play a central role in Japan.

In collaboration with the Japan Business Federation (Keidanren), a global R & D and open innovation base TIA

It is forming (from 2009). At TIA, 1. Creating Global Value, 2. Under One Roof, 3. Independence

A virtuous cycle, 4. Win-Win cooperation network, 5. Next-generation human resources development, with five principles, cooperation network with companies and universities

As a fusion base open to industry, academia and government, we will promote the industrialization of nanotechnology and human resource development in an integrated manner by promoting AI, quantum information science (QIS), and computing-based QIS, and develop and strengthen human resources. Plan and pull the industry

Prioritize research and development that provides the infrastructure that supports QIS. Sustainable and interoperable software, data maintenance and curation, and adequate security to support the research and development needed for future high-performance computing paradigms, manufacturing, devices, and architecture. Biomedical Opioid Crisis Fighting, Rapid Detection and Containment of Infectious Diseases, Drug Resistance, Prevention and Treatment of Chronic Diseases, Genetic Therapy, Neuroscience, Medical Measures and Public Health Preparation, HIV / AIDS Eradication, and More Prioritize R & D investment aimed at improving the independence, safety and health of the elderly and people with disabilities in the United States. Rapidly establish safety and efficacy for products developed using bioeconomy gene editing, adopting biotechnology products and social responsibility

Prioritize evidence-based criteria and research to promote certain uses ① "All of Us" research program (cohort study for personalized medicine)

② BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative

③ Cancer Moonshot

(4) Regenerative Medicine Innovation Project PCA in 2021 is also planned to be in these 11 areas.

① Artificial intelligence (AI)

② Computing for human interaction, communication, and ability improvement

(CHuman)

③ Computing (CNPS) to network physical systems

④ Cyber ​​Security and Privacy (CSP) Education and Human Resources (EdW)

⑥ Research and development of high-capability computing system (EHCS)

⑦ High Capability Computing Infrastructure and Applications (HCIA)

⑧ Intelligent Robotics and Autonomous System (IRAS)

⑨ Large-scale data management and analysis (LSDMA)

⑩ Large-scale network (LSN)

⑪ Software productivity / sustainability / quality (SPSQ)

Innovative Medicines Initiative (IMI) 2 Innovative Medicines 30

Electronic Components & System Initiative (ECSEL) Electronic Components & Systems 50

Clean Sky (CS) 2 Air and Air Transport 40

Fuel Cells and Hydrogen (FCH) 2 Hydrogen / Fuel Cell 13.3

Shift2Rail European single rail network 9.2

Bio-based Industries (BBI) Bio-based materials and biorefining 37

Single European Sky ATM Research (SESAR) Air Traffic Management Systems, Engineering and Physical Sciences Research Council (EPSRC), Economic and Social Research Council (ESRC), and Arts and Humanities Research Council (AHRC) Is doing only. Medical Research Council (MRC), Biotechnology and Biological Science Research Council (BBSRC), Nature

The Environmental Studies Council (NERC) not only provides research funding, but also has a research organization under its umbrella to carry out research on its own.

Giving. The Science and Technology Facility Council (STFC) manages and operates research facilities in addition to providing research funding.

ing. UKRI's 2019 budget for the study council is approximately £ 3.81 billion, using artificial intelligence (AI), data and innovation to prevent disease, diagnose early, and treat chronic illness until 2030. By 2035, at least five years longer than it is now, closing the gap between the rich and the poor

Clean growth that enables people to lead healthy and independent lives By 2030, at least halve the energy use of new buildings by 2030 Establish at least one low-carbon industrial cluster by 2040 Establish the world's first industrial cluster with zero net greenhouse gas emissions

Future Transport Means Putting the UK at the forefront of zero-emission vehicle (ZEV) design and manufacturing, 2040

Ideas for virtually zero emissions of all new cars and trucks by the year

・ Increase overall R & D investment to 2.4% of GDP by 2027

・ Increased R & D tax credit ratio to 12%

· Invested £ 725m in the Industrial Strategy Challenge Fund (ISCF)

Human resources (People)

· Invested £ 406m to promote education in STEM capabilities

・ Established a national retraining system for the digital field, etc., and built technology and digital

£ 64m investment in technical training

Infrastructure

・ Increased the National Fund for Productivity Investment (NPIF) to £ 31 billion, transportation, housing construction,

Promote investment in fields such as digital

· Electric vehicle (EV) support (£ 400 million in charging infrastructure investment and £ 100 million

Includes plug-in car grants)

-Invested over £ 1 billion to develop digital infrastructure (100 million for 5G) Business environment

・ Start and exhibition of sector agreement (government-industry alliance for the purpose of improving productivity)

Open (as of December 2019, Space, Artificial Intelligence, Automotive, Construction, Creative Industries, Rye

Agreements with 10 sectors of science, nuclear, offshore wind, rail and tourism)

· Invest over £ 20bn in innovative, high-potential businesses

・ Small and medium-sized companies, such as how to deal with the so-called "long tail" of low-productivity companies

Conducting reviews to improve corporate productivity, etc.

Formulation of regional / regional industrial strategy

・ Launched “Urban Reform Fund” for intercity transportation and invested £ 1.7 billion

・ Launched “Teacher Development Program” and invested £ 42 million in environment and energy

UK Energy Research Center (UKERC) London (Research bases are located throughout the country)

Founded in 2004. Conducting world-class research on sustainable future energy systems. It is a hub for energy research in the UK and a contact point for connecting energy research communities in the UK and abroad. It is subsidized by one of the cross-research council programs, the Energy Program for the Low Carbon Future. Life Sciences European Molecular Biology Laboratory (EMBL-EBI) Hinxton (Cambridgeshire) Established in 1992 as a division of the European Molecular Biology Laboratory (EMBL). We provide databases and conduct research related to bioinformatics. Most of the operating funds are contributed by the governments of EMBL member countries, mainly EU countries. Information Science and Technology Cambridge University Computer Laboratory Cambridge Founded in 1937. An organization at the University of Cambridge that conducts a wide range of research in areas such as computer science, engineering, technology, and mathematics. Nanotechnology and Materials Cavendish Laboratory, University of Cambridge Cambridge Founded in 1874. Institute of Physics, University of Cambridge. So far, 29 Nobel laureates have been produced. Francis Crick

James Watson discovered the double helix structure of DNA when he was at the institute, and in 1962 he won the Medical Physiology Award to improve the effectiveness of cancer treatment and strengthen cancer research to extend the life of cancer patients. To do. prevention,

Improve early detection, diagnosis and treatment. Promote the digitization of patient charts and the associated strengthening of data protection. Introduce an electronic medical record system to university hospitals in Germany by 2025. Promote plant-derived plastic production by 2025 to reduce plastic waste

Or develop substances that can be efficiently recycled, and have similar challenges.

Promote research and development by collaborating with other regions.

Aim for CO2 emissions of about 85-90% in 1990 to realize the environmental protection plan 2050

It points to the improvement of production processes and the realization of a sound-cycle economy.

Creating innovative business models through efficient resource use and digitalization

Increase productivity with.

Conduct environmental assessments using innovative tools and new indicators to protect diverse species.

This area is the beginning of major innovations such as autonomous driving, electric vehicles and fuel cell vehicles.

It has been placed. Comprehensive including charging facility development, deregulation, EU policy, etc.

Implement practical measures.

Support technology development and supply chain construction for battery production in Germany.

Bridging the gap between urban and rural areas due to changes in economic structure and demographics with the power of digital to create an environment

Improve quality of life in a thoughtful manner.

With concerns about labor shortages due to the aging of the population, assistant systems and

Use robots to reduce the burden of labor. Robo in society, including safety and health

Implement comprehensive measures such as acceptance of

② Mission in future technology

With Germany and Europe as bases for AI research and development and practical application, while securing human resources

Build an AI-based business model by involving various application areas.

③ Mission in creating an open innovation environment and entrepreneurial culture

Open access, open science, open data, open inno

Contribute to the creation of the latest science through the principle of vation. Priority technology areas

Goal Priority technology

Research with an eye on social implementation and application

Machine learning, big data

Cyber ​​security, HMI, robots, VR

Communication system, 5G communication technology

Batteries, 3D printing, weight reduction, manufacturing technology

Technology that should leap to the top of the world

Quantum simulation system, ultra-precision measurement technology, imaging

Technology

Biotechnology, bioinformatics

Aerospace satellites, materials ARENA2036 Stuttgart Great transformable automotive research

DPP RWTH Aachen University Digital Optics

Mobility2Grid Berlin Institute of Technology Smart Grid

FEN RWTH Aachen University Environmentally friendly energy

185 Cluster-Netzwerke-International

186 German name: Forschungscampus

R & D bird's-eye view report

R & D strategies of major countries (2020)

CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center

124

MODAL Humboldt Large Data Driven Transport / Medical Technology

M²OLIE Heidelberg Cancer Treatment

Open Hybrid LabFactory Braunschweig Institute of Technology Lightening research on vehicle materials

STIMULATE Magdeburg minimally invasive treatment

InfectoGnostics University of Jena Second Generation Quantum Computing (Computer, Simulation) as a priority area for early diagnosis of infectious diseases

Ration, etc.), Quantum communication (communication, security technology, etc.), measurement (precision measurement technology, etc.)

In addition to the development of technology, satellites, navigation technology, etc.), technology transfer in the quantum field and promotion of industrial participation

I'm sick. Autonomous driving, electric and fuel cell vehicles to solve social issues under "High-Tech Strategy 2025"

However, this area is at the beginning of major innovation. Maintenance of charging facilities, deregulation of laws and regulations,

In Germany, as a comprehensive practical measure including EU policy and a mission in the field of future technology

In addition, we will make Europe a base for R & D and practical application of AI, and involve various application areas while securing human resources.

Health, environment, and society that are shown to build an AI-based business model by doing so

 Health / Digital

 Digital humanity

 Social / digital security

 Digital, energy, environment, society

The 2020 plan also includes the following national priorities:

 Artificial intelligence

 Humanities and Social Sciences

 Quantum technology

 Drug resistance

 Autism in neurodevelopmental disorders

 Parallel research on rare diseases, La

Excellent based on technologies such as if science, environment / energy, ICT, and nanotechnology

The feature is that the above items are organized.

Humanities / Society, Earth System / Environmental Science, Energy, Biology / Medical, Material Science / Engineering, Astronomy / Astronomical Physics, Nuclear / High Energy Physics, ICT / Mathematics, Scientific / Technical Information While identifying 99 concrete infrastructures, it shows the direction of support. The identified infrastructure covers the fields of global systems / environmental science and biology / medical care.

There are relatively many, with 25 and 24 infrastructures specified, respectively. Humanities / Society, Earth System / Environmental Science, Energy, Biology / Medical, Material Science / Engineering, Astronomy / Astronomical Physics, Nuclear / High Energy Physics, ICT / Mathematics, Scientific / Technical Information While identifying 99 concrete infrastructures, it shows the direction of support. The identified infrastructures are relatively large in the fields of global systems / environmental science and biology / medical, with 25 and 24 infrastructures designated, respectively. A National Natural Science Fund Committee (NSFC272), the China Science and Technology Development Strategy Research Institute (CASTED273), which is a think tank for science and technology policy, and the China Science and Technology Information Institute (ISTIC274), which is responsible for building science and technology information infrastructure, are located. ing. In addition, the Chinese Academy of Sciences is under the direct control of the State Council, with 104 research institutes and two National Natural Science Foundations of China (NSFC).

Various programs including subsidies for basic research and applied research, human resource development, and base formation (under the jurisdiction and management of the National Natural Science Fund Committee under the Ministry of Science and Technology) National Science and Technology Problem-solving program for improving national competitiveness (under the jurisdiction of the State Council) National Key R & D Program National Key R & D Program of China

A program that consolidates problem-solving research funding from each ministry and agency

(Specialized research fund under the initiative of the Ministry of Science and Technology

Management and operation by the science agency 283)

④ Technology innovation guidance plan

Technology Transfer Program

⑤ Research base and human resources program

Base Kazuto Talented Research Center Grants and Human Resources Grants Program

Creation of new superiority through industrial technology system for promotion and development of ram innovation

(1) Next-generation information network technology, (2) Smart green manufacturing technology, (3)

Modern agricultural technology, ④ Modern energy technology, ⑤ Resource efficient use and environment

Protection technology, ⑥ Marine and space technology, ⑦ Smart city digital social technology

Art, ⑧ Health technology, ⑨ Modern service industry technology, ⑩ Industrial transformation technology Science and technology critical project

Implementation (a project that the government provides stable support over the long term)

(1) Research and development of large aircraft engines and gas turbines (2) Deep sea stays

③ Quantum communication and quantum computer research ④ Brain science and brain

Research (Brain Science and Brain-Inspired Intelligence Technology)

⑤ National cyber security research ⑥ Space exploration and orbital maintenance system

Research ⑦ Voluntary breeding technology ⑧ Coal clean and highly efficient utilization technology

⑨ Smart grid technology ⑩ Top-and-bottom integrated communication network technology (satellite communication and terrestrial broadcasting)

Communication integration) ⑪ Big data technology ⑫ Intelligent manufacturing and robot

Technology ⑬ Research and development and application of new materials ⑭ Hebei Regional Comprehensive Environmental Conservation

⑮ Health and welfare technology

International competitiveness of industrial technology

Improvement

(1) Advanced agricultural technology (2) Next-generation information and communication technology (3) Advanced manufacturing technology (4) New materials

Fee technology ⑤ Green and highly efficient energy technology ⑥ Advanced transportation technology ⑦

Advanced biotechnology ⑧ Advanced food manufacturing technology ⑨ For evolution of business model

Service technology that contributes ⑩ Disruptive technology that contributes to the Industrial Revolution

Improving and maintaining the standard of living

Technology system that can be continuously developed

Build

(1) Environmental and ecological conservation technology (2) Highly efficient use of resources (3) For national welfare

Contribution technology ④ Technology related to urbanization ⑤ Technology related to public safety

Techniques related to national security and national interests

Construction of surgical system

(1) Marine resource utilization technology (2) Space exploration / space development technology

③ Ultra-deep stratum development technology

Strengthening basic research ・ Strategic basic research for social needs

① Genetic improvement of living things in agriculture ② Green use of energy

Physics / Chemistry Theory for High Efficiency ③ Information for Man-Machine Fusion

Information and communication technology ④ Integrated monitoring research of the earth system ⑤ New materials

⑥ Extreme environment (large current, strong magnetic field, ultra-high)

Manufacture in (warm / ultra-low temperature) ⑦ Disasters caused by mega-projects and their

R & D bird's-eye view report

R & D strategies of major countries (2020)

CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center

180

⑧ Mechanical problems related to aircraft, rockets, and spacecraft ⑨ Medical immunity

Gaku

・ Advanced basic research

(1) Nanoscience technology (2) Quantum control and quantum information (3) Tan

Control of protein complex and life process ④ Stem cell research And to the clinic

Stagflation ⑤ Advanced research by a large research facility ⑥ Global spirit

Weather fluctuations and countermeasures ⑦ Interaction between heredity and environment in development ⑧ Synthetic organisms

Studies ⑨ Genome editing ⑩ Research on deep sea, ultra-deep strata, and space ⑪ Material depth

Layered structure and astrophysics research ⑫ Mathematics and applied mathematics ⑬ Magnetic confinement Nuclear fusion As priority fields, next-generation information and communication technology, advanced digital control machine tools and robots, aviation / U

Air equipment, marine construction machinery / high-tech vessels, advanced track transportation equipment, energy-saving / new energy vehicles,

The Chinese Academy of Sciences, Tsinghua University and Beijing University have set up the National Nanoscience Center of China, which lists power equipment, agricultural machinery equipment, new materials, biopharmaceuticals and high-performance medical equipment.

Our center is located on the premises of the Institute of Chemistry, Chinese Academy of Sciences, and nanodevices, nanomaterials, and raw materials for nanomaterials.

Body effects and safety assessment, nano characterization, nano standardization, nano manufacturing

Holds a laboratory such as Gu. Industrial informatization that controls the software industry, etc.

Department, Ministry of Science and Technology, Chinese Academy of Sciences, etc.

Policy trends include the medium- to long-term plan, strategic outline, and "scientific technology" mentioned at the beginning of this section in technological development.

An important policy is set out in "The 13th Five-Year Plan for Art Innovation". In this plan, the national critical science

"Quantum communication and quantum computer" and "National cyber seki" listed in the item of technology project

"Urity", "Tenchi integrated communication network", "Next-generation information communication" listed in the item of international competitiveness of industrial technology

"Technology", "Disruptive technology that contributes to the industrial revolution such as big data and AI", "Quantum control and quantum information" technology

is there.

From the perspective of industrial promotion, "Made in China 2025" and "Internet" announced by the State Council in July 2015.

Baidu (Baidu, Baidu, the company that provides the largest search engine in China) such as "T +" and "13th Five-Year Strategic Emerging Industry Development Plan" announced in November 2016

Build a national next-generation artificial intelligence open innovation platform

(2) Alibaba Cloud, a company under the Alibaba Group, the largest cloud service in China

By "Urban Brain" (Smart City Computational Center)

Build a national next-generation artificial intelligence open innovation platform

③ "Medical image recognition" by Tencent Co., Ltd. National next-generation artificial intelligence open innovation

Build a platform

④ Kadai Hibi Co., Ltd. (IFlytek, an artificial intelligence company in the field of speech recognition and speech synthesis established in 1999)

By "Smart Voice" National Next Generation Artificial Intelligence Open Innovation Platform

To build

⑤ "AI image processing technology" by the commercial hot spring group (SenseTime) National next-generation artificial intelligence open inno

Quantum communication / quantum computing technology to build a vation platform Nanotechnology / materials field Aerospace, orbital transportation, electronic equipment, new energy

Supplying new materials that meet the needs of industries such as motor vehicles, "C

Endo general-purpose semiconductor chips and basic software, "Very Large Scale Integration (VLSI) and software"

"Russet technology", "High-end computer, numerically controlled machine tool (CNC) and basic manufacturing technology"

Work

And autonomy

Operational standards, integrated methods, traffic management systems, defense / security luck

Deployment of autonomous driving means on the ground, in the air, and at sea, with an emphasis on development for

Prioritize R & D to lower barriers to

Advanced Manufacturing Smart Digital Manufacturing Technology, Advanced Industrial Robotics, Especially

Realized by the Internet of Things (IOT), machine learning, and AI

Research Institute, Japan Atomic Energy Agency (JAEA), Japan Aerospace Exploration Agency (JAXA), Japan Agency for Marine-Earth Science and Technology,

In addition, the former National Institute for Materials Science (NIMS) and the National Institute of Radiological Sciences (currently Department of Quantum)

The National Research Institute for Earth Science and Disaster Prevention was positioned as a part of the Academic Technology Research and Development Organization). In addition, Grants-in-Aid for Scientific Research

Japan Society for the Promotion of Science (JSPS), an independent administrative agency responsible for the distribution of money and international exchange in the academic field, and science and technology

Fundy such as Japan Science and Technology Agency (JST) 3 that implements various projects that contribute to the creation of novation

There is an institution. Regarding national university corporations, part of the National University Corporation Law has been amended4, and it has become a university in Japan.

The world's highest level of education and research activities in order to significantly improve the level of education and research and create innovation.

The Minister of Education, Culture, Sports, Science and Technology points to a national university that operates a university based on high-level goal setting so that the movement will be developed.

The "designated national university system" to be established was launched in 2017, and is currently located at Tohoku University, the University of Tokyo, Kyoto University, etc.

Seven schools, Tokyo Institute of Technology, Nagoya University, Osaka University, and Hitotsubashi University, have been designated. In addition, science and technology

Ministry of Education, Culture, Sports, Science and Technology as a national research institute that conducts research on policy and science and technology innovation

The National Institute of Science and Technology Policy (NISTEP) is located inside. Funding and industrial technology development projects

New Energy and Industrial Technology Development Organization (NEDO), the National Institute of Advanced Industrial Science and Technology under the former National Institute of Advanced Industrial Science and Technology

National Institute of Advanced Industrial Science and Technology (AIST), which was jointly and reorganized, and the economy that conducts research analysis and research on economic and industrial policies

The National Institute of Advanced Industrial Science and Technology (RIETI) can be mentioned. Of these, AIST became a "designated national research and development corporation" in 2016.

It is specified.

The Ministry of Economy, Trade and Industry also has the Japan Aerospace Exploration Agency JAXA and the Japan Agency for Medical Research and Development (AMED) with other ministries.

It is jointly under the jurisdiction.

(6) Other ministries

In addition to the Ministry of Education, Culture, Sports, Science and Technology and the Ministry of Economy, Trade and Industry, many ministries such as the Ministry of Health, Labor and Welfare and the Ministry of Agriculture, Forestry and Fisheries have announced that Science and Technology Inno

Involved in vation. Every year, the Cabinet Office is involved in science and technology related to the government, including such related ministries and agencies.

The budget is tabulated and published.

According to it, the Ministry of Education, Culture, Sports, Science and Technology and the Ministry of Economy, Trade and Industry have budgeted for science and technology for the entire government (as of the beginning of 2019).

It accounts for nearly 70%.

In 2015, the Ministry of Foreign Affairs appointed a "Minister of Foreign Affairs Science and Technology Advisor". The adviser is the Minister of Foreign Affairs

Support activities in terms of science and technology, and strengthen cooperation with science and technology advisors and stakeholders in the field of science and technology in each country

While doing so, he advises on the utilization of science and technology in the planning and drafting of various foreign policies.

(7) Headquarters established in the Cabinet

In recent years, in parallel with the system based on the Science and Technology Basic Law, the section that should be promoted comprehensively and intensively as a whole country

The basic law was enacted on the subject, and a headquarters was set up with the Prime Minister as the head and the relevant ministers as members.

The number of things to work on has increased. In science and technology, the Intellectual Property Strategy Headquarters, Umi, in relation to the Intellectual Property Basic Act

General Ocean Policy Headquarters based on the Western Basic Law, Space Development Strategy Headquarters based on the Basic Space Law, Advanced Information and Communication Network

Advanced Information and Communication Network Society Promotion Strategy Headquarters based on the Basic Law for Network Society Formation (IT Comprehensive Strategy Book)

Department), Health / Medical Strategy Promotion Headquarters based on the Health / Medical Strategy Promotion Law, etc. In July 2018

Is a cross-cutting and substantive of the Council for Science, Technology and Innovation and these headquarters, based on an integrated strategy.

The "Integrated Innovation Strategy Promotion Council" was established to make various adjustments and promote the integrated strategy.

Following the adoption of the Sustainable Development Goals (SDGs) by the United Nations, the Minister of State is a member.

The Sustainable Development Goals (SDGs) Promotion Headquarters was established in May 2016.

(8), National Institute for Materials Science, RIKEN

Tokoro, three corporations of National Institute of Advanced Industrial Science and Technology are designated as this corporation. CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center

Ten

[Chart I-4] A bird's-eye view of research funding agencies and competitive funding systems

JSPS: Japan Society for the Promotion of Science, JST: Japan Science and Technology Agency, NEDO: New Energy and Industrial Technology Development Organization,

AMED: Japan Agency for Medical Research and Development, SIP: Strategic Innovation Creation Program (Cabinet Office),

Moonshot R & D Program (Cabinet Office), COI: Center of Innovation (JST)

Source: R & D overview report "Transition of Japan's Science and Technology Innovation Policy-From the Enactment of the Science and Technology Basic Law to the Present-" (2020)

Research and Development Strategy Center)

The outline of the main funding organizations related to science and technology is as follows.

(1) Japan Society for the Promotion of Science (JSPS)

An independent administrative agency under the jurisdiction of the Ministry of Education, Culture, Sports, Science and Technology, established in 2003. Its predecessor was Japan, a foundation established in 1932.

This is the Japan Society for the Promotion of Science. As a core institution responsible for the promotion of science in Japan, Grants-in-Aid for Scientific Research (Grants-in-Aid for Scientific Research), etc.

Implemented projects such as subsidizing academic research, providing funds for training researchers, and promoting international exchange related to academics.

doing. Kakenhi has reached over 200 billion yen annually, and JSPS is Japan's largest funding machine.

Seki.

(2) Japan Science and Technology Agency (JST)

Its predecessor was the Japan Science and Technology Information Center, which was established in 1957, and the New Technology Development, which was established in 1961.

It is a special corporation science and technology promotion corporation established in 1996 with the business corporation as the parent body. Science and technology basic plan

As a core executing agency, we are implementing projects that contribute to the creation of science and technology innovation.

R & D bird's-eye view report

R & D strategies of major countries (2020)

CRDS-FY2019-FR-02 National Research and Development, Japan Science and Technology Agency Research and Development Strategy Center 11 Japan

The strategic creative research promotion project, which is the core of funding, aims to achieve the strategic goals set by the government.

Promote problem-achieving basic research and create innovative technology seeds that generate science and technology innovation

The purpose is to make it. In the future society creation business, economic and social needs are taken into consideration.

Set technically challenging goals with a clear view of targets (exit) that have an impact on

However, it can be put into practical use by utilizing promising results such as strategic creative research promotion projects and scientific research funding subsidies.

We are conducting research and development aiming at the stage where it can be determined whether or not it is possible (proof of concept: POC).

(3) National Research and Development Corporation New Energy and Industrial Technology Development Organization (NEDO)

Its predecessor was the New Energy and Industrial Technology Development Organization, which was established in 1980. Japan's largest public R & D machine

As a screwing organization, it plays a part in economic and industrial administration, "solving energy and environmental problems" and "industry".

We are working on two missions, "strengthening industrial technology."

(4) Japan Agency for Medical Research and Development (AMED)

From April 2015, conduct research and development in the medical field, improve the environment, and provide subsidies.

Established as the Japan Agency for Medical Research and Development. Health / Medical Strategy Promotion Headquarters Measures

Based on the established medical field R & D promotion plan, we will focus on nine collaborative fields such as regenerative medicine and cancer.

Promotion of consistent research and development from the basics to practical application in the medical field, smooth practical application of results, and medical field

It is supposed to comprehensively and effectively improve the environment for research and development. __ Industry-academia collaboration / regional promotion, 1) Large-scale radiation facility (SPring-8), 2) X-ray free electron laser facility (SACLA), 3) Supercomputer "K computer", 4) High-intensity proton accelerator facility (J- Four PARC) facilities have been designated and are supported by the government.

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Utilizing the technology and know-how built up at Cambridge University, MIT University oxford University, Harvard University, University of Tokyo, Osaka University, etc., using the original strains that have been passed down and bred for over 100 years, medical proteins Produce with high yield and highest quality. Works with many companies and researchers to produce refractory proteins for use in medicines that are important to modern medicine. In addition, by developing poorly expressed proteins, we will challenge vaccines against unknown viruses that will be encountered in the future. We aim to develop and innovate life science and healthcare by fusing cutting-edge technologies such as optics, information science, and biotechnology. We aim to realize new drug discovery screening, cell therapy and medical diagnosis by machine learning-driven high-content cell optical measurement and real-time image-based cell sorting technology. With the development of advanced technology and the accelerating progress of precision and individualization of medical care, it is required to put into practical use tests and diagnostic technologies with high clinical value so that they can contribute to the provision of more accurate diagnosis and optimal treatment. I am. In addition, digitalization efforts in the medical field, such as online medical care, image diagnosis using AI, and automation of examinations using robots, are progressing rapidly. .. So far, we have been acquiring technology to analyze cells, genes, and proteins with high accuracy and sensitivity. Among these, the cell analysis platform has already been applied to various Sysmex products, but in addition to the conventional high-speed cell classification, high-precision cell classification using various information such as the function and reactivity of cells is performed. We are developing technology to achieve both. We possess "ghost cytometry technology" * 1 that enables simple and high-speed acquisition of detailed cell morphology information. The amount of information obtained by this technology is much larger than that of conventional flow cytometry tests, and as a result, it is possible to obtain more accurate cell morphology information. If this technology can capture the detailed characteristics and functions of each cell in addition to the number and morphology of the cells, it is very effective in grasping the pathological condition using a sample such as blood. It can be expected to contribute not only to improving the accuracy of general diagnosis but also to personalized medicine. As the feasibility of diagnostic technology with high clinical value utilizing "ghost cytometry technology" has increased, blood etc. will be used to promote joint development of new AI-based cell analysis technology ahead of the rest of the world. In the cell analysis (including research use) in the in-vitro diagnostic area used, we will carry out joint development for the practical application of cell analyzers and testing methods that utilize "ghost cytometry technology". We aim to contribute to the development and evolution of medical care in the world by developing new cell analysis technology and testing methods by integrating our unique knowledge and technology and our unique technology "ghost cytometry technology". Design the evolution of health care. Is our mission, and we are contributing to the development of medical care and the healthy lives of people. We consistently carry out research and development, manufacturing, sales, service and support of equipment, reagents, and software necessary for sample testing that collects and examines blood and urine, and delivers products to medical institutions in more than 190 countries and regions. We are delivering. In recent years, we have expanded our business to the life science field, creating new testing and diagnostic value using our unique technology, and contributing to the realization of optimal medical care for each individual, the reduction of the burden on patients, and the improvement of QOL. I am aiming to do it. Based on the "ghost cytometry technology" that was born, we are a venture company that aims to develop and innovate life science and medical care. By using this basic technology, we aim to realize new regenerative / cell medicine, drug discovery, and medical test diagnosis, and contribute to innovative treatment and diagnosis. Research and development of drug discovery / diagnosis platform by image recognition type high-speed cell sorting technology utilizing AI
* 1 Ghost cytometry technology:
A new method of flow cytometry that enables high-speed, high-precision analysis and discrimination of cells of similar size with small differences in morphology. Cell morphology information measured as an optical compression signal is directly analyzed and discriminated in real time without imaging using machine learning. A technology that enables selective and high-speed separation of target cells in a flow path by combining with fluid technology.
② <High-speed, high-precision cell analysis / discrimination / separation (image) by ghost cytometry>
The company is creating the basic concepts and technologies of biotechnology, medicine, mathematical information computing science, and engineering necessary for this realization. Research and development, manufacturing, sales, and measurement consulting for shape / deformation / strain distribution measurement equipment. Using moiré fringe analysis technology, we perform infrastructure measurement, electronic component measurement, vibration measurement, board measurement, etc. We are aiming to realize cell therapy that suppresses autoimmune diseases and rejection during transplantation using immunosuppressive cells called regulatory T cells (Tregs). Our unique Treg cell product "ULTRA-iTreg" is a technology for producing a large amount of stable Tregs, and we are developing it to contribute to the fundamental treatment of inflammatory diseases. We will establish a technology to use T cells as a drug and provide cancer immunotherapy that can be used "for anyone" and "immediately". We have the technology to regenerate T cells from pluripotent stem cells such as iPS cells and ES cells. Using this method, we are developing a strategy to mass-produce killer T cells that can kill cancer and use them to treat cancer. We will promote the practical development of cell medicine containing iPS cell-derived nephron progenitor cells as an active ingredient, and aim to obtain approval for regenerative medicine products for the indication of chronic kidney disease (CKD). By delaying the decline in renal function of patients, it is expected that the transition to artificial dialysis will be suppressed and the QOL will be improved.
(3) We are developing a blood glucose monitoring system for home use. We aim to provide the world's first micro / non-invasive glycemic monitoring system for people with diabetes / preliminary group to make glycemic control more accessible. Established technology for inducing iPS cells to differentiate into nephron progenitor cells with high efficiency, expansion culture technology, etc.
④ For corneal endothelium diseases in the field of ophthalmology 1) Fuchs endothelial corneal dystrophy (FECD) instillation drug 2) Research, development and commercialization of two pipelines of products such as regenerative medicine for corneal endothelium treatment To make it.

(5) Based on the two technologies of original genome (DNA) editing and the world's first RNA editing using PPR protein, our business is to contribute to the development of the world bio industry. The strength of our basic technology lies in the ability to theoretically design protein molecules that bind to the desired DNA or RNA sequence, and by creating applications that can control genes and gene expression at various stages, medical care and agriculture. , Expected to expand into various industries such as material production. Craif has developed a device that efficiently captures exosomes from body fluids using zinc oxide nanowires, and has the technology to extract miRNA with high efficiency. We have found that cancer can be detected with high accuracy by measuring the expression pattern of urinary miRNA in cancer patients using this technology and analyzing it by machine learning. Toward this practical application, we are developing a test to detect more than 10 types of cancer from just one drop of urine with high accuracy and early detection unlike any other in the world. It is a peptide that has been reported to have a remarkable healing (regeneration) effect on the intestinal mucosa on intractable inflammatory bowel disease. Based on this research, the company is aiming to eliminate unmet medical needs by developing new drugs with a completely different approach from existing drugs.
(5) Aiming to develop and commercialize a breast diagnostic imaging device that uses ultrasound The device under development is an existing device that automatically captures a three-dimensional image of the entire breast using ultrasound without compressing the breast. Compared to breast diagnostic imaging equipment, there is no risk of pain or exposure, and it is possible to acquire highly reproducible data. By realizing women-friendly tests, we aim to contribute to improving the breast cancer screening rate and early detection. Breast cancer, which affects one in nine women Breast cancer is increasing year by year in both the number of affected and the number of deaths. Currently, the number of affected people is about 96,000 and the number of deaths is about 15,000.
* 1 From the National Cancer Center Cancer Control Information Center "Cancer Information Service"
* 2 From the vital statistics of the Ministry of Health, Labor and Welfare
 
Peak morbidity is in the 40s
Breast cancer has a peak prevalence in the late 40s.
Breast cancer is also the leading cause of cancer death in this generation.
 
High survival rate with early detection and treatment
Breast cancer is a cancer with a high survival rate if it is detected early and treated early.
However, if detection and treatment are delayed and metastases to major organs, the survival rate will decrease.
* 3 From the Japanese Breast Cancer Society "National Breast Cancer Patient Registration Survey Report No. 29"
 
What you can do for early detection of breast cancer
53% of Breast Cancer Detections Are Self-Discovery
There is data that more than half of breast cancer detections are self-aware. *Four
There is a lump inside the breast, there is a twitch or color change on the skin, there is some secretion from the nipple.
It is effective for early detection of breast cancer to be aware of small changes by making a habit of self-checking on a daily basis.
* 4 National Breast Cancer Patient Registration Survey Report 2016 Cases
 
It is important to have a breast cancer screening that suits you
The Ministry of Health, Labor and Welfare has established a guideline that "women aged 40 and over should be interviewed and have a mammography examination once every two years."
Mammography can detect small calcified tumors that are not noticeable to the touch and is useful for early detection of breast cancer.
However, on the other hand, women with a high proportion of well-developed mammary glands (statistics show that it is more common among young women and especially among Asians, and about 80% of Asian women under the age of 50 have a high proportion of breasts. There is also data called "breast (dense breast)" * 5), which has the disadvantage that it is difficult to distinguish breast cancer because the mammary glands and tumors appear white.
Unfortunately, many Japanese women are relatively young and suffer from breast cancer.
If you are young or your doctor has pointed out that your breast ratio is high, you should consult with your doctor about a combination of echo (ultrasound) tests that are not affected by your breast ratio. In addition, since the current general echo examination requires a high level of skill for the surgeon, it is recommended to select a medical institution specializing in mammary glands that has a skilled specialist.
* 5 From Annals of Internal Medicine, 2008 Mar 4; 148 (5): 337–347.
 
Aiming to develop women-friendly devices
-Development of diagnostic imaging equipment for breasts using ultrasound-
The ring echo to be developed is an innovative breast diagnostic imaging device that uses an ultrasonic transducer based on medical ultrasonic technology.
We are proceeding with development with the cooperation of academic institutions and medical institutions such as the University of Tokyo.
* Technology that enables uniform and high-resolution imaging by arranging ultrasonic transducers in a ring shape
Aiming for Breast Cancer Examination We aim to realize a female-friendly ultrasonic diagnostic imaging device for breasts. Just put your breasts in the holes in the bed ...
• You can have your breasts examined without anyone seeing or touching them
• Since it is an ultrasound, there is no need to worry about radiation exposure, and it is suitable for examinations for people with high mammary gland density.
• No compression, so you can get a 3D image of the entire breast that is close to its natural shape
• Improve the accuracy of diagnosis with technology that supports diagnosis
Image of use
When the examinee lies down and puts the breast in the hole in the bed, the annular ultrasonic transducer moves up and down to take an image of the inside of the breast.
Since the oscillator does not touch the body, the examinee does not feel any pain during shooting.
In addition, since the image is taken with the breast hanging down, highly reproducible photography is possible.
 


⑥ Both our 1-channel electrosurgical sleep scope and sleep analysis program SEAS-G @ Cloud have received regulatory certification, and their safety and performance have been trusted by clinicians and researchers, and numerous papers have been reported. There is. Similar to the conventional sleep test, it is a system based on the world standard brain wave, but the idea of ​​development is completely different. User-friendly brain waves The meter enables measurement at home, collects a large amount of data by being able to measure easily, and has realized the development of a data-driven analysis system. We will expand the challenge of contributing to society from Japan to the world through the provision of a scientific sleep evaluation system.
⑦ Utilizing our unique basic technology of creating three-dimensional tissues / organs only from cells, we can regenerate tissues / organs that have become dysfunctional due to illness or injury, and be satisfied with conventional surgery and treatment methods. It is a regenerative medicine venture that aims to contribute to many patients by responding to unmet needs that have not existed.
Cyfuse is working on the practical application of breakthrough cell products in the field of regenerative medicine and cell medicine using bio 3D printers.

⑧ We have both synthesis technology and analysis technology for sugar chain related substances, and we also have a wide range of biochemical experiment technology. While aiming for drug discovery with glycopeptides and anti-glycopeptide antibodies, making full use of four core technologies: 1) GlycoBlotting method, 2) glycopeptide synthesis, 3) fine particle preparation technology, and 4) glycopeptide array, regarding sugar chains We can meet all needs. By providing the standard of sugar chain science, we will contribute to the development of life science and aim to contribute to the healthy life of people. Advanced measurement and analysis technology equipment development business




⑨ Development of focused ultrasonic therapy device (treatment device) With the vision of "bringing a new future to cancer patients with acoustic engineering (ultrasonic)", "cancer", especially "pancreatic cancer" which is an intractable cancer We are developing for the target. The developed genome analysis technology is the only single-cell genome analysis technology for microorganisms in the world. This technology has made it possible to decipher the genomic information of microorganisms that live in all environments on the earth from a single cell with high accuracy. With this technology, it is possible to acquire unknown microbial genome information at high speed and comprehensively without the need for complicated isolation / culture required in conventional microbiome research or calculation processing of complicated sequence data. have become. We provide this technology as a next-generation microbiota analysis service, and realize our mission "Unlock the Potential of Microbes" through collaboration with all microbial-related companies and academia, mainly in the medical and agricultural fields. , We will provide unprecedented value to society.
⑩ In the main pharmaceutical field, we are conducting research and development of skin ulcer therapeutic agents and antibody-inducing peptides. The skin ulcer therapeutic agent is expected to be a unique wound therapeutic agent having both antibacterial activity and wound healing promoting effect. In addition, antibody-induced peptides have low manufacturing costs, can be inexpensive alternatives to antibody drugs, and utilize cutting-edge technology based on robotics engineering research to solve the problems of conventional prostheses and realize natural movements. Produces a compact and lightweight high-performance artificial leg.
⑪ The purpose is to provide safe and secure food materials derived from natural products, functional ingredients such as foods and cosmetics, food additives, pharmaceutical raw materials, biofuels, etc. that meet customer needs by utilizing microalgae. ..

⑫ We develop, manufacture and sell next-generation organic EL materials used for organic EL displays and lighting. Based on the technology licensed from Kyushu University and Harvard University, we are working on the development of Hyperfluorescence / TADF light emission technology that realizes all of the long-life, high-purity color development and high-efficiency light emission with excellent cost performance without relying on rare metals. Aiming to commercialize the world's first Hyperfluorescence technology
⑬ We are developing smart apparel (clothing type wearable devices) globally. Currently, he is developing products and services that provide fun and convenience in daily life, such as watching over babies, comfortable sleep solutions, and fitness. In the future, by analyzing and utilizing the biometric data collected from these services, we aim to develop services that are more valuable to users and apply them to preventive medicine such as prediction of myocardial infarction to realize a safe and secure society. .. We started a business in the development, manufacture and sale of low-temperature sintered silver nanoparticle ink for printed electronics, and based on that technology, we will actively work on the development of sensor devices manufactured by printing. So far, we have commercialized a film-type high-sensitivity bed sensor that can "subtly" monitor the heartbeat, respiration, and sleep depth of a sleeping person.
Currently, we are promoting demonstrations and development of applications in the field of nursing care and medical care toward the commercialization of this bed sensor. A research and development venture company that creates elemental technologies for "Virtual Live Clinic". It is a business platform where people all over the world can enjoy and practice optimal health promotion and disease prevention / treatment for individuals "anytime", "anywhere", and "everyone".
⑭ Operation of robot facility for life science experiment work
Development, sales and maintenance of robots and robot peripherals
Data and Intellectual Property Management and Utilization of Life Science Experiments Life science experiments rely on tacit knowledge based on the skills and accumulated knowledge of skilled researchers. This situation causes blurring of the experimental results of each experimenter and difficulty in handing over the technique, which hinders the realization of reproducibility. You can set the experimental operation in millimeters or seconds. By creating a protocol that quantifies the skills and tacit knowledge of experienced researchers, it is possible to transfer "techniques" and turn them into general-purpose "techniques." Quantifying and universalizing techniques and knowledge will lead to innovation in society.
⑮ The current situation is that life science experiments rely on tacit knowledge based on the skills and accumulated knowledge of skilled researchers. This situation causes blurring of the experimental results of each experimenter and difficulty in handing over the technique, which hinders the realization of reproducibility. You can set the experimental operation in millimeters or seconds. By creating a protocol that quantifies the skills and tacit knowledge of experienced researchers,